cyclophilin

[US]/ˌsɪkləʊˈfɪlɪn/
[UK]/ˌsaɪkloʊˈfɪlɪn/
Frequency: Very High

Translation

n.Any of a family of proteins that bind to cyclosporine and possess peptidyl-prolyl isomerase activity.

Phrases & Collocations

cyclophilin a

cyclophilin b

cyclophilin d

cyclophilin inhibitor

cyclophilin binding

cyclophilin activity

cyclophilin gene

cyclophilin expression

cyclophilin proteins

cyclophilin complex

Example Sentences

cyclophilin a is a key mediator in the immunosuppressive action of cyclosporine.

cyclophilin d plays a critical role in mitochondrial permeability transition.

the cyclophilin inhibitor prevented tissue damage in the experiment.

researchers studied cyclophilin expression in cancer cells.

cyclophilin binding to cyclosporine triggers immunosuppression.

elevated cyclophilin levels have been detected in various tumors.

cyclophilin a contributes to protein folding in the cell.

the cyclophilin gene mutation caused metabolic disorders.

mitochondrial cyclophilin regulates cell death pathways.

cyclophilin activity can be measured using biochemical assays.

targeting cyclophilin may offer new therapeutic approaches.

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