lithiation process
锂化过程
lithiation mechanism
锂化机理
lithiation kinetics
锂化动力学
lithiation state
锂化状态
lithiation reaction
锂化反应
lithiation degree
锂化程度
lithiation capacity
锂化容量
lithiation rate
锂化速率
during lithiation
在锂化过程中
deep lithiation
深度锂化
direct lithiation of benzene derivatives requires strong bases like n-butyllithium at low temperatures.
直接锂化苯衍生物需要强碱，如正丁基锂，并在低温下进行。
the lithiation protocol was optimized to achieve regioselective functionalization of the heterocyclic compound.
优化了锂化方案，以实现对杂环化合物的区域选择性官能化。
metal-halogen exchange provides a complementary approach to directed ortho-lithiation for aryl halides.
金属-卤素交换为芳基卤代物的定向邻位锂化提供了一种补充方法。
the lithiation mechanism involves deprotonation of the acidic proton adjacent to a coordinating group.
锂化机制涉及靠近配位基团的酸性质子的去质子化。
optimized lithiation conditions using tmeda as an additive significantly improved the reaction yield.
使用tmeda作为添加剂的优化锂化条件显著提高了反应产率。
regioselective lithiation of pyridine allows for the synthesis of valuable 2-substituted derivatives.
吡啶的区域选择性锂化允许合成有价值的2-取代衍生物。
the efficiency of lithiation depends on the choice of base, solvent, and reaction temperature.
锂化的效率取决于碱、溶剂和反应温度的选择。
in situ trapping of the organolithium intermediate with electrophiles provides access to diverse products.
原位捕获带有亲电试剂的有机锂中间体，可获得各种各样的产品。
directed ortho-lithiation is a powerful strategy for the functionalization of aromatic compounds.
定向邻位锂化是芳香化合物官能化的有力策略。
lithiation of the carbonyl compound followed by quenching with deuterium oxide introduces a deuterium label.
羰基化合物的锂化，然后用重水淬灭，引入了重氢标记。
the stability of organolithium reagents necessitates careful control of reaction conditions.
有机锂试剂的稳定性需要仔细控制反应条件。
comparative lithiation studies revealed significant differences in reactivity between analogous substrates.
比较锂化研究表明，类似底物之间的反应活性存在显着差异。
lithiation process
锂化过程
lithiation mechanism
锂化机理
lithiation kinetics
锂化动力学
lithiation state
锂化状态
lithiation reaction
锂化反应
lithiation degree
锂化程度
lithiation capacity
锂化容量
lithiation rate
锂化速率
during lithiation
在锂化过程中
deep lithiation
深度锂化
direct lithiation of benzene derivatives requires strong bases like n-butyllithium at low temperatures.
直接锂化苯衍生物需要强碱，如正丁基锂，并在低温下进行。
the lithiation protocol was optimized to achieve regioselective functionalization of the heterocyclic compound.
优化了锂化方案，以实现对杂环化合物的区域选择性官能化。
metal-halogen exchange provides a complementary approach to directed ortho-lithiation for aryl halides.
金属-卤素交换为芳基卤代物的定向邻位锂化提供了一种补充方法。
the lithiation mechanism involves deprotonation of the acidic proton adjacent to a coordinating group.
锂化机制涉及靠近配位基团的酸性质子的去质子化。
optimized lithiation conditions using tmeda as an additive significantly improved the reaction yield.
使用tmeda作为添加剂的优化锂化条件显著提高了反应产率。
regioselective lithiation of pyridine allows for the synthesis of valuable 2-substituted derivatives.
吡啶的区域选择性锂化允许合成有价值的2-取代衍生物。
the efficiency of lithiation depends on the choice of base, solvent, and reaction temperature.
锂化的效率取决于碱、溶剂和反应温度的选择。
in situ trapping of the organolithium intermediate with electrophiles provides access to diverse products.
原位捕获带有亲电试剂的有机锂中间体，可获得各种各样的产品。
directed ortho-lithiation is a powerful strategy for the functionalization of aromatic compounds.
定向邻位锂化是芳香化合物官能化的有力策略。
lithiation of the carbonyl compound followed by quenching with deuterium oxide introduces a deuterium label.
羰基化合物的锂化，然后用重水淬灭，引入了重氢标记。
the stability of organolithium reagents necessitates careful control of reaction conditions.
有机锂试剂的稳定性需要仔细控制反应条件。
comparative lithiation studies revealed significant differences in reactivity between analogous substrates.
比较锂化研究表明，类似底物之间的反应活性存在显着差异。
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